sORF-encoded polypeptide SEP1 is a novel virulence factor of Phytophthora pathogens.
Identifieur interne : 000002 ( Main/Exploration ); précédent : 000001; suivant : 000003sORF-encoded polypeptide SEP1 is a novel virulence factor of Phytophthora pathogens.
Auteurs : Nan Wang [République populaire de Chine] ; Zhiyuan Yin [République populaire de Chine] ; Weiwei Duan [République populaire de Chine] ; Xiong Zhang [République populaire de Chine, Oman] ; Lei Pi [Oman] ; Yifang Zhang [Oman] ; Daolong Dou [République populaire de Chine]Source :
- Molecular plant-microbe interactions : MPMI [ 0894-0282 ] ; 2020.
Abstract
Diseases caused by the notorious Phytophthora species result in enormous economic losses to crops and forests. Increasing evidence suggests that small open reading frame-encoded polypeptides (SEPs) participate in environmental responses of animals, plants, and fungi. However, it remains largely unknown whether Phytophthora pathogens produce SEPs. Here, we systematically predicted and identified 96 SEP candidates in P. capsici. Among them, three may induce stable cell death in Nicotiana benthamiana. Phytophthora-specific and conserved SEP1 facilitated P. capsici infection. PcSEP1-induced cell death is BAK1- and SOBIR1-independent and is correlated to its virulence function. Finally, PcSEP1 may be targeted to the apoplast for carrying out its functions, for which the C-terminus is indispensable. Together, our results demonstrated that SEP1 is a new virulence factor, and previously unknown SEPs may act as effector proteins in Phytophthora pathogens.
DOI: 10.1094/MPMI-06-20-0160-R
PubMed: 33103962
Affiliations:
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wang.nan@cau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>China Agricultural University, 34752, Department of Plant Pathology, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Yin, Zhiyuan" sort="Yin, Zhiyuan" uniqKey="Yin Z" first="Zhiyuan" last="Yin">Zhiyuan Yin</name><affiliation wicri:level="3"><nlm:affiliation>China Agricultural University, 34752, Department of Plant Pathology, Beijing, China; zyin@cau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>China Agricultural University, 34752, Department of Plant Pathology, Beijing</wicri:regionArea><placeName><settlement type="city">Pékin</settlement></placeName></affiliation></author><author><name sortKey="Duan, Weiwei" sort="Duan, Weiwei" uniqKey="Duan W" first="Weiwei" last="Duan">Weiwei Duan</name><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University, 70578, Department of Plant Pathology, Nanjing, Jiangsu, China; 2018102044@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Nanjing Agricultural University, 70578, Department of Plant Pathology, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Xiong" sort="Zhang, Xiong" uniqKey="Zhang X" first="Xiong" last="Zhang">Xiong Zhang</name><affiliation wicri:level="1"><nlm:affiliation>China Agricultural University, 34752, Beijing, Department of Plant Pathology, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>China Agricultural University, 34752, Beijing, Department of Plant Pathology</wicri:regionArea><wicri:noRegion>Department of Plant Pathology</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Nanjing Agricultural University, 70578, Nanjing, China; hbzhangxiong@126.com.</nlm:affiliation><country wicri:rule="url">Oman</country><wicri:regionArea>Nanjing Agricultural University, 70578, Nanjing</wicri:regionArea><wicri:noRegion>Nanjing</wicri:noRegion></affiliation></author><author><name sortKey="Pi, Lei" sort="Pi, Lei" uniqKey="Pi L" first="Lei" last="Pi">Lei Pi</name><affiliation wicri:level="3"><nlm:affiliation>China Agricultural University, 34752, Department of Plant Pathology, Beijing, China; 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ddou@njau.edu.cn.</nlm:affiliation><country wicri:rule="url">République populaire de Chine</country><wicri:regionArea>Nanjing Agricutural University, The department of plant pathology, Nanjing, Jiangsu</wicri:regionArea><wicri:noRegion>Jiangsu</wicri:noRegion></affiliation></author></analytic><series><title level="j">Molecular plant-microbe interactions : MPMI</title><idno type="ISSN">0894-0282</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Diseases caused by the notorious Phytophthora species result in enormous economic losses to crops and forests. Increasing evidence suggests that small open reading frame-encoded polypeptides (SEPs) participate in environmental responses of animals, plants, and fungi. However, it remains largely unknown whether Phytophthora pathogens produce SEPs. Here, we systematically predicted and identified 96 SEP candidates in P. capsici. Among them, three may induce stable cell death in Nicotiana benthamiana. Phytophthora-specific and conserved SEP1 facilitated P. capsici infection. PcSEP1-induced cell death is BAK1- and SOBIR1-independent and is correlated to its virulence function. Finally, PcSEP1 may be targeted to the apoplast for carrying out its functions, for which the C-terminus is indispensable. Together, our results demonstrated that SEP1 is a new virulence factor, and previously unknown SEPs may act as effector proteins in Phytophthora pathogens.</div></front></TEI><pubmed><MedlineCitation Status="Publisher" Owner="NLM"><PMID Version="1">33103962</PMID><DateRevised><Year>2020</Year><Month>10</Month><Day>26</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0894-0282</ISSN><JournalIssue CitedMedium="Print"><PubDate><Year>2020</Year><Month>Oct</Month><Day>26</Day></PubDate></JournalIssue><Title>Molecular plant-microbe interactions : MPMI</Title><ISOAbbreviation>Mol Plant Microbe Interact</ISOAbbreviation></Journal><ArticleTitle>sORF-encoded polypeptide SEP1 is a novel virulence factor of Phytophthora pathogens.</ArticleTitle><ELocationID EIdType="doi" ValidYN="Y">10.1094/MPMI-06-20-0160-R</ELocationID><Abstract><AbstractText>Diseases caused by the notorious Phytophthora species result in enormous economic losses to crops and forests. Increasing evidence suggests that small open reading frame-encoded polypeptides (SEPs) participate in environmental responses of animals, plants, and fungi. However, it remains largely unknown whether Phytophthora pathogens produce SEPs. Here, we systematically predicted and identified 96 SEP candidates in P. capsici. Among them, three may induce stable cell death in Nicotiana benthamiana. Phytophthora-specific and conserved SEP1 facilitated P. capsici infection. PcSEP1-induced cell death is BAK1- and SOBIR1-independent and is correlated to its virulence function. Finally, PcSEP1 may be targeted to the apoplast for carrying out its functions, for which the C-terminus is indispensable. Together, our results demonstrated that SEP1 is a new virulence factor, and previously unknown SEPs may act as effector proteins in Phytophthora pathogens.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Wang</LastName><ForeName>Nan</ForeName><Initials>N</Initials><AffiliationInfo><Affiliation>China Agricultural University, 34752, Department of Plant Pathology, Beijing, China; wang.nan@cau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Yin</LastName><ForeName>Zhiyuan</ForeName><Initials>Z</Initials><AffiliationInfo><Affiliation>China Agricultural University, 34752, Department of Plant Pathology, Beijing, China; zyin@cau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Duan</LastName><ForeName>Weiwei</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>Nanjing Agricultural University, 70578, Department of Plant Pathology, Nanjing, Jiangsu, China; 2018102044@njau.edu.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Xiong</ForeName><Initials>X</Initials><AffiliationInfo><Affiliation>China Agricultural University, 34752, Beijing, Department of Plant Pathology, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Nanjing Agricultural University, 70578, Nanjing, China; hbzhangxiong@126.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Pi</LastName><ForeName>Lei</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>China Agricultural University, 34752, Department of Plant Pathology, Beijing, China; pl18320722339@163.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhang</LastName><ForeName>Yifang</ForeName><Initials>Y</Initials><AffiliationInfo><Affiliation>China Agricultural University, 34752, Department of Plant Pathology, Beijing, China; zyf787794882@163.com.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dou</LastName><ForeName>Daolong</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>China Agricultural University, 34752, Department of Plant Pathology, Beijing, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Nanjing Agricutural University, The department of plant pathology, Nanjing, Jiangsu, China; ddou@njau.edu.cn.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>10</Month><Day>26</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Mol Plant Microbe Interact</MedlineTA><NlmUniqueID>9107902</NlmUniqueID><ISSNLinking>0894-0282</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>10</Month><Day>26</Day><Hour>12</Hour><Minute>9</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>10</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>10</Month><Day>27</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>aheadofprint</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">33103962</ArticleId><ArticleId IdType="doi">10.1094/MPMI-06-20-0160-R</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Oman</li><li>République populaire de Chine</li></country><settlement><li>Pékin</li></settlement></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Wang, Nan" sort="Wang, Nan" uniqKey="Wang N" first="Nan" last="Wang">Nan Wang</name></noRegion><name sortKey="Dou, Daolong" sort="Dou, Daolong" uniqKey="Dou D" first="Daolong" last="Dou">Daolong Dou</name><name sortKey="Dou, Daolong" sort="Dou, Daolong" uniqKey="Dou D" first="Daolong" last="Dou">Daolong Dou</name><name sortKey="Duan, Weiwei" sort="Duan, Weiwei" uniqKey="Duan W" first="Weiwei" last="Duan">Weiwei Duan</name><name sortKey="Yin, Zhiyuan" sort="Yin, Zhiyuan" uniqKey="Yin Z" first="Zhiyuan" last="Yin">Zhiyuan Yin</name><name sortKey="Zhang, Xiong" sort="Zhang, Xiong" uniqKey="Zhang X" first="Xiong" last="Zhang">Xiong Zhang</name></country><country name="Oman"><noRegion><name sortKey="Zhang, Xiong" sort="Zhang, Xiong" uniqKey="Zhang X" first="Xiong" last="Zhang">Xiong Zhang</name></noRegion><name sortKey="Pi, Lei" sort="Pi, Lei" uniqKey="Pi L" first="Lei" last="Pi">Lei Pi</name><name sortKey="Zhang, Yifang" sort="Zhang, Yifang" uniqKey="Zhang Y" first="Yifang" last="Zhang">Yifang Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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